Steven M. Muskal

Steven M. Muskal, Ph.D.

AI Pioneer | Drug Discovery Expert | Creative Innovator | Serial Inventor

CEO of Eidogen-Sertanty with over 40 years at the intersection of AI, chemistry, biology, and drug discovery. Host of the Renaissance Circle podcast. Builder of AI-Steve, Food Health: Scan and Score, and AI-Dad.

Professional Excellence

Current Leadership

Chief Executive Officer - Eidogen-Sertanty
Leading the development of innovative AI-driven solutions for drug discovery and computational chemistry, bridging the gap between molecular science and practical therapeutic applications.

Areas of Expertise

Career Highlights

Distinguished Career Path

Education

Deep Dive Audio

Listen to audio versions of my articles and insights. Each Substack article has an accompanying audio deep dive.

🎧 Site Overview Audio

Get a complete audio summary of my work, research, and creative projects.

Renaissance Circle Network Renaissance Circle Podcast Renaissance Circle Network

Steven M. Muskal, Ph.D. - AI Pioneer, Drug Discovery Expert, Innovator, and Musician
Explores science, business, and the art of feeling good.
Where innovators, scientists, and entrepreneurs discuss the future of health and performance

🎙️ Latest: The Birth of AI Steve - Skating to Where the Puck Is Going

A 1991 PhD thesis on neural networks for protein structure - thirty-three years before AlphaFold's Nobel. The pattern of dopamine-driven curiosity, and the through-line from AI-Dad to Toast Our Friend to Food Health to AI-Steve - all under The Governed Loop.

The Birth of AI Steve - Skating to Where the Puck Is Going
Read on Substack → Read on Medium → Watch on YouTube →

Featured Projects

All projects →
AI-Steve
AI & Productivity

AI-Steve

Personal research and coaching assistant grounded in PostgreSQL embeddings of email, calendar, photos, and chats.

Food Health: Scan and Score
Health Tech

Food Health: Scan and Score

iOS and Android app turning meals into structured nutrition data via photo capture and AI analysis.

Food Health TxD
Health Tech

Food Health TxD

Diabetes-aware companion to Scan and Score: AI carb and macro estimation paired with continuous glucose monitor data.

AI-Dad
AI & Productivity

AI-Dad

Conversational AI that preserves voice, wisdom, and stories across generations.

Recent Articles

All articles →
The Birth of AI Steve - Skating to Where the Puck Is Going
AI

The Birth of AI Steve

From a 1991 PhD thesis on neural networks for protein structure to AlphaFold's Nobel - and the through-line from AI-Dad to Toast Our Friend to Food Health to AI-Steve, all under The Governed Loop.

Too Big to Fail?
AI

Too Big to Fail?

AI became cognitive infrastructure. The dopamine pull behind it, and how to keep your instincts sharp.

The Metabolic Crisis Is Not a News Story
Health

The Metabolic Crisis Is Not a News Story

93% of American adults carry a metabolic risk factor. Measurement, CGMs, and social networks are how reversal scales.

AI Steve II: The Governed Loop
AI

AI Steve II: The Governed Loop

An AI that proposes its own extensions but waits for human approval - and redirects amplified time toward deeper work.

Music & Creative Sessions

All sessions →

Drumming, recording, and creative collaborations from my home music studio. Each week, different combinations of musicians are invited for Mix-n-Match sessions.

Watch Sessions

Example Presentations

Recent

My 38-Year Journey with Neural Networks: Can They Further Unlock Pichia's Potential?

Conference presentation on the application of neural networks to unlock the potential of Pichia pastoris in biotechnology and protein expression systems.

Blast From The Past

Historic Presentation from 2010 (15+ years ago. Always on the "bleeding edge...")

A look back at research and insights from 2010.

View Publications & Presentations →