Steven M. Muskal

Steven M. Muskal, Ph.D.

AI Pioneer | Drug Discovery Expert | Creative Innovator | Serial Inventor

CEO of Eidogen-Sertanty with over 40 years at the intersection of AI, chemistry, biology, and drug discovery. Host of the Renaissance Circle podcast. Builder of AI-Steve, Food Health AI, and AI-Dad.

Articles

Essays, podcast episodes, and conversations from Renaissance Circle - Dr. Steven Muskal's Substack. AI, health, drug discovery, music, and the art of feeling good.

All AI Health Podcast Family Music
Are We There Yet?
AI

Are We There Yet?

When a single person can operate like an army, the real question isn't capability - it's judgment.

Apr 22, 2026

Food Is Medicine
Health

Food Is Medicine. But First It Has to Become Data.

Improving health starts with real food quality, practical tracking, and consistent habits.

Mar 8, 2026

AGI
AI

We've Already Reached AGI. The Market Just Hasn't Admitted It Yet.

The Zero to One moment already happened. What markets are pricing now is One to N.

Feb 2026

N-of-1 Health Stack
Health

The N-of-1 Health Stack

Why personal data, not population averages, should drive health insight.

Feb 2026

AI-Steve Deep Dive
AI

AI-Steve Deep Dive

When personal AI becomes an extension of intellect.

Jan 30, 2026

Curiosity
Podcast

Curiosity Is the Only Sustainable Edge

New episode on the power of curiosity.

Jan 2026

Constraint
Podcast

When Constraint Becomes a Superpower

Steve talks with Gibson Hanks on constraint as creative leverage.

Dec 18, 2025

Christmas Lights
AI

Christmas Lights, The Beetle and Recursion

Intelligence lives in the in-between.

Nov 14, 2025

AI-Dad
AI

AI-Dad: Preserving Legacy Through Conversational Intelligence

Building an AI to keep wisdom, voice, and love alive.

Oct 14, 2025

Community
Podcast

Community is the Moat

Steve sits with Lloyed Lobo, cofounder of Boast.ai and Traction.

Sep 2025

Behind the Bar
Podcast

Behind the Bar, Ahead of the Curve

Life lessons of Dakota and Vlad.

Aug 17, 2025

Grit
Podcast

Grit, Curiosity & Building What Matters

From biomedical roots to bold ideas with Megan Phillips and Fernanda Campos.

Jul 23, 2025

Glucose Grit
Podcast

Glucose, Grit & Breaking Glass Ceilings

Personal passion, professional pivots, and mastering medical devices with Christy Shearer.

Jun 27, 2025

Music Security Meaning
Music

Music, Security, and Meaning

Steve and Dom Mather explore cybersecurity, music, and the search for balance.

May 30, 2025

Science Startups
Podcast

Science, Startups, and Serendipity

Full raw session with Devon Cayer.

Apr 29, 2025

Homeownership Healthcare AI
Family

Homeownership, Healthcare, and AI

Will the next generation be better off?

Mar 28, 2025

Writers AI
AI

Will Writers Hold the Key to AI?

Artificial intelligence, education, and the future of expertise.

Feb 28, 2025

Inside the Story
Podcast

Inside the Story: Pro Tips from Scott Miller

The art of storytelling and life lessons.

Jan 13, 2025

Healing Music
Music

Healing through music

Steve and Jerome Dawson explore the power of music to heal.

Nov 16, 2024

Two Founders
Podcast

Two founders recount their unexpected career paths

Life lessons on repurposing skills for new career paths.

Oct 31, 2024

Quarter Century Neil
Podcast

A Quarter Century+: Talking with Neil Peretz

It's good to have entrepreneurial friends in your 20-30's.

Sep 13, 2024

Do You Have Grit
Family

Do You Have Grit?

What's something you did as a kid that was strange?

Sep 6, 2024

Father Daughter Part 2
Family

Father-Daughter Face-Off (part two): Medical Training Overseas

"OG" Great-Grandma Helen.

Jul 30, 2024

Father Daughter Part 1
Family

Father-Daughter Face-Off (part one): Comparing Gen-X and Gen-Z

Deep dive summary across generations.

Jul 24, 2024

Optimizing Sleep
Health

Optimizing Sleep: Measure to Manage

The biggest room in my house is the room for improvement.

Jun 28, 2024

Mitochondrial Journey
Health

My Story: A Mitochondrial Journey

Most of my mitochondrial-sharing ancestors are no longer with us.

Jun 9, 2024

Sleep Go-Tos
Health

Sleep Optimization Go-To's

A growing list of go-tos for sleep optimization et al.

Jun 9, 2024

Welcome
Welcome

Welcome to Renaissance Circle

Your no-hidden-agenda source for health, music, and entrepreneurial insight.

May 30, 2024